Maximizing human developmental
potential

Within EU-funded Horizon 2020 projects, ‘Deliverables’ are “outputs that must be produced at a given moment” during the project. This includes, for example, the project website itself, detailed information on the scientific progress of a specific task, a research manuscript, an in-depth report, a software tool, or another important “building block”. As soon as such a deliverable has been completed, a deliverable report is required to be submitted to the European Commission (EC). The reports of work packages (WPs) 1, 2, 12, and 13 are confidential, but some reports of WPs 3, 4, 5, 6, 7, 8, 9, 10, and 11 are public. Once these public deliverable reports are ready, we make them available here, so feel free to view or download them as you like.

WP1 – Integrating and harmonizing data

• D1.3 – Recommendations for approaches and methods for designing, performing and maintaining pregnancy and child cohort studies

WP3 – Integrating early-life stressors

• D3.5 – Report on patterns of core and integrated socio-economic, migration-, urban environment- and lifestyle-related stressors across Europe
• D3.6 – Report on exposome models based on proof-of-principle studies

WP4 – Early-life stressors & cardiometabolic health life course trajectories

• D4.1 – Report on cardiovascular developmental trajectories during fetal life, infancy, and early childhood, and the relationship with early-life exposures and cardiovascular risk factors in childhood
• D4.2 – Report on the relationships of early-life exposures with trajectories of cardiovascular and metabolic risk factors from birth to adulthood
• D4.3 – Report on various life-course models for the effects of early-life exposures on later cardio-metabolic risk factors and disease

WP5 – Early-life stressors & respiratory health life course trajectories

• D5.1 – Report on the associations of early-life stressors during preconception, pregnancy, infancy, and early childhood with lung function developmental trajectories and the risk of asthma from childhood until young adulthood
• D5.2 – Report on early-life stressors that are related to both asthma throughout childhood and lung function and COPD in adulthood
• D5.3 – Report on the relationships of early-life stressors with transient and persistent common allergies, and the extent to which these mediate associations of early-life stressors with life-course chronic obstructive respiratory health and disease trajectories

WP6 – Early-life stressors & mental health life course trajectories

• D6.1 – Report on internalizing and externalizing behavior and other mental health trajectories from birth to childhood, and their associations with psychopathology outcomes
• D6.2 – Report on the effects of early-life stressors on mental health and psychopathology life-course trajectories

WP7 – Methods for causal inference & life course trajectory analyses

• D7.1 – Report on approaches for causal inference in the context of life-course trajectory analyses
• D7.2 – Report on approaches for longitudinal data/health trajectories in the context of life-course analyses
• D7.3 – Report on approaches to analyse multiple stressor data in the context of longitudinal modelling

WP8 – DNA methylation & gene expression in life course health trajectories

• D8.2 – Report on associations of early-life stressors with DNA methylation at birth
• D8.3 – Report on the persistence of DNA methylation differences related to early-life stressors

WP9 – Early intervention strategies focused on early-life stressors

• D9.2 – Report on review of interventions focused on socio-economic stressors, to improve life-course health trajectories
• D9.3 – Report on review of interventions focused on migration stressors, to improve life-course health trajectories
• D9.4 – Report on review of interventions focused on urban environment stressors, to improve life-course health trajectories
• D9.5 – Report on review of interventions focused on lifestyle stressors, to improve life-course health trajectories

WP10 – Economic, public, and individual impact of early-life stressors

• coming soon

WP11 – Dissemination, exploitation, and training

• D11.1 – External project website launched