Maximizing human developmental
potential

Publications

Here, you can view the most recent findings and publications of the LifeCycle research team. Just click on the respective title to read or download the original article.

Number of LifeCyle publications to date: 215

2022

  1. Bond TA et al. (2022). Exploring the causal effect of maternal pregnancy adiposity on offspring adiposity: Mendelian randomization using polygenic risk scores. BMC Medicine 20, Article number: 34.
  2. Elhakeem A et al. (2022). Using linear and natural cubic splines, SITAR, and latent trajectory models to characterise nonlinear longitudinal growth trajectories in cohort studies. BMC Medical Research Methodology 22, Article number: 68.
  3. Fernandez-Barres S et al. (2022). Urban environment and health behaviours in children from six European countries. Environ Int 165: 107319.
  4. Pinot de Moira A et al. (2022). Associations of early-life pet ownership with asthma and allergic sensitization: A meta-analysis of more than 77,000 children from the EU Child Cohort Network. J Allergy Clin Immunol 150(1): 82-92.

2021

  1. Ardura-Garcia C et al. (2021). ERS International Congress 2020: highlights from the Paediatric Assembly. ERJ Open Res 7(1).
  2. Bell JA et al. (2021). Sex differences in systemic metabolites at four life stages: cohort study with repeated metabolomics. BMC Med 19(1): 58.
  3. Birks LE et al. (2021). Radiofrequency electromagnetic fields from mobile communication: Description of modeled dose in brain regions and the body in European children and adolescents. Environ Res 193: 110505.
  4. Brands B et al. (2021). Global e-Learning in Early Nutrition and Lifestyle for International Healthcare Professionals: Design and Evaluation of the Early Nutrition Specialist Programme (ENS). Nutrients 13(3).
  5. Cadman T et al. (2021). Joint associations of parental personality traits and socio‐economic position with trajectories of offspring depression: Findings from up to 6925 families in a UK birth cohort. JCPP Advances 1(3): e12028.
  6. Cadman T et al. (2021). The role of school enjoyment and connectedness in the association between depressive and externalising symptoms and academic attainment: Findings from a UK prospective cohort study. J Affect Disord 295: 974-980.
  7. Chen LW et al. (2021). Associations of maternal dietary inflammatory potential and quality with offspring birth outcomes: An individual participant data pooled analysis of 7 European cohorts in the ALPHABET consortium. PLoS Med 18(1): e1003491.
  8. Chen LW et al. (2021). Maternal dietary quality, inflammatory potential and childhood adiposity: an individual participant data pooled analysis of seven European cohorts in the ALPHABET consortium. BMC Med 19(1): 33.
  9. Choedon T et al. (2021). Population estimates and determinants of severe maternal thinness in India. Int J Gynaecol Obstet 155(3): 380-397.
  10. de Prado-Bert P et al. (2021). The early-life exposome and epigenetic age acceleration in children. Environ Int 155: 106683.
  11. Eriksson MD et al. (2021). Higher carotid-radial pulse wave velocity is associated with non-melancholic depressive symptoms in men – findings from Helsinki Birth Cohort Study. Ann Med 53(1): 531-40.
  12. Florian S et al. (2021). Parental migrant status and health inequalities at birth: The role of immigrant educational selectivity. Soc Sci Med 278: 113915.
  13. Geurtsen ML et al. (2021). Associations Between Intake of Sugar-Containing Beverages in Infancy With Liver Fat Accumulation at School Age. Hepatology 73(2): 560-70.
  14. Geurtsen ML et al. (2021). Maternal Early-Pregnancy Glucose Concentrations and Liver Fat Among School-Age Children. Hepatology.
  15. Gomez-Alonso MDC et al. (2021). DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures. Clin Epigenetics 13(1): 7.
  16. Gonzalez J. et al (2021). Metabolomic Signatures in Pediatric Crohn’s Disease Patients with Mild or Quiescent Disease Treated with Partial Enteral Nutrition: A Feasibility Study. SLAS TECHNOLOGY 26(2): 165-177
  17. Guerlich K et al. (2021). Sleep duration and problem behaviour in 8-year-old children in the Childhood Obesity Project. Eur Child Adolesc Psychiatry.
  18. Hartwig FP et al. (2021). Bias in two-sample Mendelian randomization when using heritable covariable-adjusted summary associations. Int J Epidemiol.
  19. Huang RC et al. (2021). Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors. Epigenetics: 1-18.
  20. Hu C et al. (2021). A population-based study on associations of stool microbiota with atopic diseases in school-age children. J Allergy Clin Immunol 148(2): 612-20.
  21. Hu C et al. (2021). Association between nasal and nasopharyngeal bacterial colonization in early life and eczema phenotypes. Clin Exp Allergy 51(5): 716-25.
  22. Hughes RA et al. (2021). Combining Longitudinal Data From Different Cohorts to Examine the Life-Course Trajectory. Am J Epidemiol.
  23. Jacob CM et al. (2021). A systematic review and meta-analysis of school-based interventions with health education to reduce body mass index in adolescents aged 10 to 19 years. Int J Behav Nutr Phys Act 18(1): 1.
  24. Jacob CM et al. (2021). Test, Trace and Learn: lessons about COVID-19 from young people Testare, tracciare e imparare: lezioni sul COVID-19 dai giovani. Epidemiol Prev 45(6): 441-442.
  25. Julvez J et al. (2021). Early life multiple exposures and child cognitive function: A multi-centric birth cohort study in six European countries. Environ Pollut 284: 117404.
  26. Kurilshikov A et al. (2021). Large-scale association analyses identify host factors influencing human gut microbiome composition. Nat Genet 53(2): 156-65.
  27. Larrosa S. et al (2021). Fibre Intake Is Associated with Cardiovascular Health in European Children. Nutrients 13(1):12.
  28. Looman KIM et al. (2021). Increased Th22 cell numbers in a general pediatric population with filaggrin haploinsufficiency: The Generation R Study. Pediatr Allergy Immunol 32(6): 1360-8.
  29. Lubczynska MJ et al. (2021). Air pollution exposure during pregnancy and childhood and brain morphology in preadolescents. Environ Res 198: 110446.
  30. Luo M et al. (2021). Neonatal DNA methylation and childhood low prosocial behavior: An epigenome-wide association meta-analysis. Am J Med Genet B Neuropsychiatr Genet 186(4): 228-41.
  31. Maitre L et al. (2021). Early-life environmental exposure determinants of child behavior in Europe: A longitudinal, population-based study. Environ Int 153: 106523.
  32. Mensink-Bout SM et al. (2021). Cardio-metabolic risk factors during childhood in relation to lung function and asthma. Pediatr Allergy Immunol 32(5): 945-52.
  33. Moccia C et al. (2021). Birthweight DNA methylation signatures in infant saliva. Clin Epigenetics 13(1): 57.
  34. Modi N et al. (2021). Health of women and children is central to covid-19 recovery. BMJ 373: n899.
  35. Monasso GS et al. (2021). Associations of circulating folate, vitamin B12 and homocysteine concentrations in early pregnancy and cord blood with epigenetic gestational age: the Generation R Study. Clin Epigenetics 13(1): 95.
  36. Monasso GS et al. (2021). Associations of Early Pregnancy and Neonatal Circulating Folate, Vitamin B-12, and Homocysteine Concentrations with Cardiometabolic Risk Factors in Children at 10 y of Age. J Nutr 151(6): 1628-36.
  37. Mulder RH et al. (2021). Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence. Hum Mol Genet 30(1): 119-34.
  38. Nader JL et al. (2021). Cohort description: Measures of early-life behaviour and later psychopathology in the LifeCycle Project – EU Child Cohort Network. J Epidemiol.  Online ahead of print.
  39. Nedelec R et al. (2021). Maternal and infant prediction of the child BMI trajectories; studies across two generations of Northern Finland birth cohorts. Int J Obes (Lond) 45(2): 404-14.
  40. Penkler M et al. (2021). Developmental Origins of Health and Disease, resilience and social justice in the COVID era. J Dev Orig Health Dis. Online ahead of print.
  41. Penova-Veselinovic B et al. (2021). DNA methylation patterns within whole blood of adolescents born from assisted reproductive technology are not different from adolescents born from natural conception. Hum Reprod 36(7): 2035-49.
  42. Pinot de Moira A et al. (2021). The EU Child Cohort Network’s core data: establishing a set of findable, accessible, interoperable and re-usable (FAIR) variables. Eur J Epidemiol 36(5): 565-80.
  43. Polanska K et al. (2021). Dietary Quality and Dietary Inflammatory Potential During Pregnancy and Offspring Emotional and Behavioral Symptoms in Childhood: An Individual Participant Data Meta-analysis of Four European Cohorts. Biol Psychiatry 89(6): 550-9.
  44. Popovic M et al. (2021). Determination of saliva epigenetic age in infancy, and its association with parental socio-economic characteristics and pregnancy outcomes. J Dev Orig Health Dis, 12(2), 319-327.
  45. Quezada-Pinedo HG et al. (2021). Maternal iron status during early pregnancy and school-age, lung function, asthma, and allergy: The Generation R Study. Pediatr Pulmonol 56(6): 1771-8.
  46. Quezada-Pinedo HG et al. (2021). Maternal Iron Status in Pregnancy and Child Health Outcomes after Birth: A Systematic Review and Meta-Analysis. Nutrients 13(7).
  47. Rasella D et al. (2021). Developing an integrated microsimulation model for the impact of fiscal policies on child health in Europe: the example of childhood obesity in Italy. BMC Med 19(1): 310.
  48. Rijlaarsdam J et al. (2021). Genome-wide DNA methylation patterns associated with general psychopathology in children. J Psychiatr Res 140: 214-20.
  49. Ronkainen J et al. (2021). Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium. Epigenetics: 1-13.
  50. Sammallahti S et al. (2021). Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation. Mol Psychiatry 26(6): 1832-45.
  51. Sethi V et al. (2021). Screening and management options for severe thinness during pregnancy in India. Int J Gynaecol Obstet 155(3): 357-379.
  52. Sharp GC et al. (2021). Paternal body mass index and offspring DNA methylation: findings from the PACE consortium. Int J Epidemiol 50(4): 1297-315.
  53. Taylor K et al. (2021). Effect of Maternal Prepregnancy/Early-Pregnancy Body Mass Index and Pregnancy Smoking and Alcohol on Congenital Heart Diseases: A Parental Negative Control Study. J Am Heart Assoc 10(11): e020051.
  54. van den Dries MA et al. (2021). Prenatal Exposure to Nonpersistent Chemical Mixtures and Fetal Growth: A Population-Based Study. Environ Health Perspect 129(11): 117008.
  55. van Dongen J et al. (2021). DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan. Mol Psychiatry 26(6): 2148-62.
  56. Vehmeijer FOL et al. (2021). Associations of Hair Cortisol Concentrations With Cardiometabolic Risk Factors in Childhood. J Clin Endocrinol Metab 106(9): e3400-e13.
  57. Warembourg C et al. (2021). Urban environment during early-life and blood pressure in young children. Environ Int 146: 106174.
  58. Wiertsema CJ et al. (2021). First trimester fetal proportion volumetric measurements using a Virtual Reality approach. Prenat Diagn 41(7): 868-76.
  59. Zou R et al. (2021). Maternal polyunsaturated fatty acids during pregnancy and offspring brain development in childhood. Am J Clin Nutr 114(1): 124-33.

2020

  1. Al Rashid K et al. (2020). Association of the serum metabolomic profile by nuclear magnetic resonance spectroscopy with sperm parameters: a cross-sectional study of 325 men. F S Sci 1(2): 142-60.
  2. Beaumont RN et al. (2020). Common maternal and fetal genetic variants show expected polygenic effects on risk of small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies. PLoS Genet 16(12): e1009191.
  3. Bjerregaard LG et al. (2020). Possible Modifiers of the Association Between Change in Weight Status From Child Through Adult Ages and Later Risk of Type 2 Diabetes. Diabetes Care 43(5): 1000-7.
  4. Cabre-Riera A et al. (2020). Estimated whole-brain and lobe-specific radiofrequency electromagnetic fields doses and brain volumes in preadolescents. Environ Int 142: 105808.
  5. Caramaschi D. et al. (2020). Epigenome-wide association study of seizures in childhood and adolescence. Clin Epigenetics. 12(1): 8.
  6. Dall’ Aglio L et al. (2020). Epigenome-wide associations between observed maternal sensitivity and offspring DNA methylation: a population-based prospective study in children. Psychol Med: 1-11.
  7. Ehakeem A et al. (2020). Age at puberty and accelerometer-measured physical activity: Findings from two independent UK cohorts. Ann Hum Biol 47(4): 391-9.
  8. El Marroun H et al. (2020). Association of Gestational Age at Birth With Brain Morphometry. JAMA Pediatr 174(12): 1149-58.
  9. Geurtsen ML et al. (2020). Associations of maternal early-pregnancy blood glucose and insulin concentrations with DNA methylation in newborns. Clin Epigenetics 12(1): 134.
  10. Hamoen M et al. (2020). Development of a prediction model to target screening for high blood pressure in children. Prev Med 132: 105997.
  11. Hanson M. et al. (2020). New guidelines, position paper, and insights from the FIGO Pregnancy Obesity and Nutrition Initiative (PONI). Int J Gynaecol Obstet. 151(S1), 1-3.
  12. Hu C et al. (2020). Associations of eczema phenotypes with emotional and behavioural problems from birth until school age. The Generation R Study. Br J Dermatol 183(2): 311-20.
  13. Hu C et al. (2020). Eczema phenotypes and risk of allergic and respiratory conditions in school age children. Clin Transl Allergy 10: 7.
  14. Jacob C.M. et al. (2020). Building resilient societies after COVID-19 requires multifaceted investment targeting maternal, neonatal and child health. Lancet Public Health. Online first: 21 September 2020.
  15. Jacob C.M. et al. (2020). Implications of the Developmental Origins of Health and Disease (DOHaD) concept for policy-making. Curr Opin Endocr Metab Res. 13: 20-27.
  16. Jacob C.M. et al. (2020). Prevention on non-communicable diseases by interventions in the preconception period: A FIGO position paper for action by the healthcare practitioners. Int J Gynaecol Obstet. 151(S1), 6-15.
  17. Jaddoe V.W.V. et al. (2020). The LifeCycle Project-EU Child Cohort Network: a federated analysis infrastructure and harmonized data of more than 250,000 children and parents. Eur J Epidemiol. 35(7): 709-724.
  18. Kirchberg F.F. et al. (2020). Impact of infant protein supply and other early life factors on plasma metabolome at 5.5 and 8 years of age: a randomized trial. Int J Obesity. 44: 69-81.
  19. Koopman-Verhoeff ME et al. (2020). Genome-wide DNA methylation patterns associated with sleep and mental health in children: a population-based study. J Child Psychol Psychiatry 61(10): 1061-9.
  20. Looman KIM et al. (2020). Associations of Th2, Th17, Treg cells, and IgA(+) memory B cells with atopic disease in children: The Generation R Study. Allergy 75(1): 178-87.
  21. Lowry E et al. (2020). Early exposure to social disadvantages and later life body mass index beyond genetic predisposition in three generations of Finnish birth cohorts. BMC Public Health 20(1): 708.
  22. Lubczynska M.J. et al. (2020). Exposure to Air Pollution during Pregnancy and Childhood, and White Matter Microstructure in Preadolescents. Environ Health Perspect. 128(2): 27005.
  23. Mensink-Bout SM et al. (2020). Associations of Plasma Fatty Acid Patterns during Pregnancy with Respiratory and Allergy Outcomes at School Age. Nutrients 12(10).
  24. Merid SK et al. (2020). Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age. Genome Med 12(1): 25.
  25. Mikkola T.M. et al. (2020). Associations of Fat and Lean Body Mass with Circulating Amino Acids in Older Men and Women. J Gerontol A Biol Sci Med Sci. 75(5): 885-891.
  26. Mikkola T.M. et al. (2020). Body composition and changes in health-related quality of life in older age: a 10-year follow-up of the Helsinki Birth Cohort Study. Qual Life Res. [e-pub ahead of print].
  27. Monasso GS et al. (2020). Timing- and Dose-Specific Associations of Prenatal Smoke Exposure With Newborn DNA Methylation. Nicotine Tob Res 22(10): 1917-22.
  28. Mulder R.H. et al. (2020). Epigenomics of being bullied: changes in DNA methylation following bullying exposure. Epigenetics. 1-15.
  29. Neumann A et al. (2020). Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis. Transl Psychiatry 10(1): 398.
  30. Palaniswamy S et al. (2020). Could vitamin D reduce obesity-associated inflammation? Observational and Mendelian randomization study. Am J Clin Nutr 111(5): 1036-47.
  31. Parmar P et al. (2020). Understanding the cumulative risk of maternal prenatal biopsychosocial factors on birth weight: a DynaHEALTH study on two birth cohorts. J Epidemiol Community Health 74(11): 933-41.
  32. Philips EM et al. (2020). Changes in parental smoking during pregnancy and risks of adverse birth outcomes and childhood overweight in Europe and North America: An individual participant data meta-analysis of 229,000 singleton births. PLoS Med 17(8): e1003182.
  33. Pizzi C. et al. (2020). Measuring Child Socio-Economic Position in Birth Cohort Research: The Development of a Novel Standardized Household Income Indicator. Int J Environ Res Public Health. 17(5): 1700.
  34. Pizzi C et al. (2020). Socioeconomic inequalities in reproductive outcomes in the Italian NINFEA birth cohort and the Piedmont Birth Registry [Disuguaglianze socioeconomiche negli esiti riproduttivi nella coorte italiana di nuovi nati NINFEA e nel Registro delle nascite piemontese.] Epidemiol Prev 44(5-6 Suppl 1): 136-41.
  35. Rauschert S et al. (2020). Machine learning and clinical epigenetics: a review of challenges for diagnosis and classification. Clin Epigenetics 12(1): 51.
  36. Rauschert S et al. (2020). Machine Learning-Based DNA Methylation Score for Fetal Exposure to Maternal Smoking: Development and Validation in Samples Collected from Adolescents and Adults. Environ Health Perspect 128(9): 97003.
  37. Robinson O et al. (2020). Determinants of accelerated metabolomic and epigenetic aging in a UK cohort. Aging Cell 19(6): e13149.
  38. Santos S. et al. (2020). Applying the exposome concept in birth cohort research: a review of statistical approaches. Eur J Epidemiol. 35: 193–204.
  39. Selenius JS et al. (2020). Impaired glucose regulation, depressive symptoms, and health-related quality of life. BMJ Open Diabetes Res Care 8(1).
  40. Shokry E et al. (2020). Impact of Treatment with RUTF on Plasma Lipid Profiles of Severely Malnourished Pakistani Children. Nutrients 12(7).
  41. Theurich MA et al. (2020). Nutritional Adequacy of Commercial Complementary Cereals in Germany. Nutrients 12(6).
  42. Toemen L et al. (2020). Body Fat Distribution, Overweight, and Cardiac Structures in School-Age Children: A Population-Based Cardiac Magnetic Resonance Imaging Study. J Am Heart Assoc 9(13): e014933.
  43. van den Dries MA et al. (2020). Phthalate and Bisphenol Exposure during Pregnancy and Offspring Nonverbal IQ. Environ Health Perspect 128(7): 77009.
  44. van den Dries MA et al. (2020). Prenatal exposure to organophosphate pesticides and brain morphology and white matter microstructure in preadolescents. Environ Res 191: 110047.
  45. van Meel ER et al. (2020). The influence of Epstein-Barr virus and cytomegalovirus on childhood respiratory health: A population-based prospective cohort study. Clin Exp Allergy 50(4): 499-507.
  46. van Meel ER et al. (2020). Parental psychological distress during pregnancy and the risk of childhood lower lung function and asthma: a population-based prospective cohort study. Thorax 75(12): 1074-81.
  47. Vehmeijer FOL et al. (2021). Associations of Hair Cortisol Concentrations with General and Organ Fat Measures in Childhood. J Clin Endocrinol Metab 106(2): e551-e61.
  48. Vehmeijer FOL et al. (2020). DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies. Genome Med 12(1): 105.
  49. Voerman E. et al. (2020). A population-based resource for intergenerational metabolomics analyses in pregnant women and their children: the Generation R Study. Metabolomics 16(4): 43.
  50. Vogelezang S et al. (2020). Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits. PLoS Genet 16(10): e1008718.
  51. Yeung EH et al. (2020). Cord blood DNA methylation reflects cord blood C-reactive protein levels but not maternal levels: a longitudinal study and meta-analysis. Clin Epigenetics 12(1): 60.
  52. Zheng Y et al. (2020). Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood. Eur J Epidemiol 35(7): 685-97.
  53. Zou R. et al. (2020). A prospective population-based study of gestational vitamin D status and brain morphology in preadolescents. Neuroimage. 209: 116514.
  54. Neumann A. et al. (2020). Association between DNA methylation and ADHD symptoms from birth to school age: A prospective meta-analysis. Translational Psychiatry Volume 10, Article number: 398.

2019

  1. Alemany S. et al. (2019). Common Polygenic Variations for Psychiatric Disorders and Cognition in Relation to Brain Morphology in the General Pediatric Population. J Am Acad Child Adolesc Psychiatry. Online first: S0890-8567(19)30007-3.
  2. Aubert A.M. et al. (2019). Deriving the Dietary Approaches to Stop Hypertension (DASH) Score in Women from Seven Pregnancy Cohorts from the European ALPHABET Consortium. Nutrients 11(11): E2706.
  3. Ballon M. et al. (2019). Which modifiable prenatal factors mediate the relation between socio-economic position and a child’s weight and length at birth? Matern Child Nutr 15(4): e12878.
  4. Bird P.K. et al. (2019). Income inequality and social gradients in children’s height: a comparison of cohort studies from five high-income countries. BMJ Paediatr Open 3(1): e000568
  5. Birth-Gene Study Working Group et al. (2019). Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study. JAMA Netw Open 2(9): e1910915.
  6. Bond T.A. et al. (2019). Exploring the role of genetic confounding in the association between maternal and offspring body mass index: evidence from three birth cohorts. Int J Epidemiol: dyz095.
  7. Bradfield J.P. et al. (2019). A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity. Hum Mol Genet. 28(19): 3327-3338.
  8. Brand J.S. et al. (2019). Associations of maternal quitting, reducing, and continuing smoking during pregnancy with longitudinal fetal growth: Findings from Mendelian randomization and parental negative control studies. PLoS Med 16(11): e1002972.
  9. Cardenas A. et al. (2019). Prenatal maternal antidepressants, anxiety, and depression and offspring DNA methylation: epigenome-wide associations at birth and persistence into early childhood. Clin Epigenetics 11(1): 56.
  10. Chandni M.J. (2019). Do the concepts of “life course approach” and “developmental origins of health and disease” underpin current maternity care? Study protocol. Int J Gynaecol Obstet 147(2): 140-146.
  11. Cortes Hidalgo A.P. et al. (2019). Observed infant-parent attachment and brain morphology in middle childhood- A population-based study. Dev Cogn Neurosci 40: 100724.
  12. Couto Alves A. et al. (2019). GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. Sci Adv 5(9): eaaw3095.
  13. den Dekker H.T. et al. (2019). Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course. Eur Respir J 53(4): 1801795.
  14. Elhakeem A. (2019). Association Between Age at Puberty and Bone Accrual From 10 to 25 Years of Age. JAMA Netw Open 2(8): e198918.
  15. Geurtsen M.L. (2019). Newborn and childhood differential DNA methylation and liver fat in school-age children. Clin Epigenetics 12(1): 3.
  16. Gruzieva O. et al. (2019). Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis. Environ Health Perspect 127(5): 57012.
  17. Haworth S. et al. (2019). Low-frequency variation in TP53 has large effects on head circumference and intracranial volume. Nat Commun 10(1): 357.
  18. Hwang L.D. et al. (2019). Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight. Int J Epidemiol. 48(5): 1457-1467.
  19. Hu C et al. (2019). Most associations of early-life environmental exposures and genetic risk factors poorly differentiate between eczema phenotypes: the Generation R Study. Br J Dermatol 181(6): 1190-7.
  20. Jacob C.M. et al. (2019). What quantitative and qualitative methods have been developed to measure the implementation of a life-course approach in public health policies at the national level? in Health Evidence Network synthesis report 63. Copenhagen. Publisher: WHO Europe.
  21. Jacob C.M. et al. (2019). Do the concepts of “life course approach” and “developmental origins of health and disease” underpin current maternity care? Study protocol. Int J Gynaecol Obstet 147(2): 140-146.
  22. Jacob C.M., Newell M.L., and Hanson M. (2019). Narrative review of reviews of preconception interventions to prevent an increased risk of obesity and non-communicable diseases in children. Obes Rev 20, Suppl 1: 5-17.
  23. Juonala M. et al. (2019). A Cross-Cohort Study Examining the Associations of Metabolomic Profile and Subclinical Atherosclerosis in Children and Their Parents: The Child Health CheckPoint Study and Avon Longitudinal Study of Parents and Children. J Am Heart Assoc 8(14): e011852.
  24. Kazmi N. et al. (2019). Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns. Hypertension 74(2): 375-383.
  25. Kirchberg F.F. et al. (2019). Are All Breast-fed Infants Equal? Clustering Metabolomics Data to Identify Predictive Risk Clusters for Childhood Obesity. J Pediatr Gastroenterol Nutr 68(3): 408-415.
  26. Koletzko B. et al. (2019). Nutrition During Pregnancy, Lactation and Early Childhood and its Implications for Maternal and Long-Term Child Health. Ann Nutr Metab 74: 93–106.
  27. Küpers L.K. et al. (2019). Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birth weight. Nat Commun 10: 1893.
  28. LifeCycle Project – Maternal Obesity and Childhood Outcomes Study Group et al. (2019). Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes. JAMA 321(17): 1702-1715.
  29. Liu J. et al. (2019). An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis. Nat Commun 10(1): 2581.
  30. Maas S.C.E. et al. (2019). Validated inference of smoking habits from blood with a finite DNA methylation marker set. Eur J Epidemiol 34(11): 1055-1074.
  31. Marchioro L. et al. (2019). Effect of a low glycaemic index diet during pregnancy on maternal and cord blood metabolomic profiles: results from the ROLO randomized controlled trial. Nutr Metab (Lond) 16: 59
  32. Marchioro L. et al. (2019). Caesarean section, but not induction of labor, is associated with major changes in cord blood metabolome. Sci Rep 9(1): 17562.
  33. Markovic M et al. (2019). Prenatal exposure to non-steroidal anti-inflammatory drugs (NSAIDs) and neurodevelopmental outcomes in children. Pharmacoepidemiol Drug Saf 28(4): 452-9.
  34. Middeldorp C. M. et al. (2019). The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects. Eur J Epidemiol 34 (3): 279–300.
  35. Mikkola T. (2019). Physical heaviness of work and sitting at work as predictors of mortality: a 26-year follow-up of the Helsinki Birth Cohort Study. BMJ Open 9: e026280.
  36. Miliku K. et al. (2019). Associations of maternal and fetal vitamin D status with childhood body composition and cardiovascular risk factors. Matern Child Nutr 15(2): e12672.
  37. Mills H.L. et al. (2019). The effect of a lifestyle intervention in obese pregnant women on gestational metabolic profiles: findings from the UK Pregnancies Better Eating and Activity Trial (UPBEAT) randomised controlled trial. BMC Med 17(1): 15.
  38. Muetzel RL et al. (2019). Frequent Bullying Involvement and Brain Morphology in Children. Front Psychiatry 10: 696.
  39. Pearce N., Vandenbroucke J.P., and Lawlor D.A. (2019). Causal Inference in Environmental Epidemiology: Old and New Approaches. Epidemiology 30(3): 311-316.
  40. Popovic M. et al. (2019). Differentially methylated DNA regions in early childhood wheezing: An epigenome‐wide study using saliva. Pediatr Allergy Immunol 30: 305– 314
  41. Poulsen G. et al. (2019). Does smoking during pregnancy mediate educational disparities in preterm delivery? Findings from three large birth cohorts. Paediatr Perinat Epidemiol 33: 164– 171.
  42. Rantalainen V et al. (2019). APOE varepsilon4, rs405509, and rs440446 promoter and intron-1 polymorphisms and dementia risk in a cohort of elderly Finns-Helsinki Birth Cohort Study. Neurobiol Aging 73: 230 e5- e8.
  43. Reese S.E. et al. (2019). Epigenome-wide meta-analysis of DNA methylation and childhood asthma. J Allergy Clin Immunol 143(6): 2062–2074.
  44. Richiardi L. et al. (2019). Baseline selection on a collider: a ubiquitous mechanism occurring in both representative and selected cohort studies. J Epidemiol Community Health 73: 475-480.
  45. Richiardi L (2019). [Research question and study validity] Il quesito di ricerca e la validita degli studi. Epidemiol Prev 43(4): 217-9.
  46. Rodriguez A et al. (2019). Antenatal corticosteroid therapy (ACT) and size at birth: A population-based analysis using the Finnish Medical Birth Register. PLoS Med 16(2): e1002746.
  47. Ronkainen J et al. (2019). Maternal hemoglobin associates with preterm delivery and small for gestational age in two Finnish birth cohorts. Eur J Obstet Gynecol Reprod Biol 238: 44-8.
  48. Santos S. et al. (2019). Maternal body mass index, gestational weight gain, and childhood abdominal, pericardial and liver fat assessed by magnetic resonance imaging. Int J Obes 43(3): 581-593.
  49. Santos S. et al. (2019). Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta-analysis of European, North American, and Australian cohorts. BJOG 126(8): 984-995.
  50. Santos S. et al. (2019). Sources of confounding in life course epidemiology. J Dev Orig Health Dis 10(3): 299-305.
  51. Sikdar S. et al. (2019). Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking. Epigenomics 11(13): 1487-500.
  52. Stott J et al. (2019). Cognitive mediation in people with dementia: Development, structural, and construct validity of the first dementia-specific measure. Int J Geriatr Psychiatry 34(11): 1590-8.
  53. Teumer A. et al. (2019). Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Nat Commun 10(1): 4130.
  54. Theurich M.A. et al. (2019). Commercial complementary food use amongst European infants and children: results from the EU Childhood Obesity Project. Eur J Nutr 59: 1679–1692.
  55. Thyssen J.P. et al. (2019). Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis. Allergy 75(6): 1481-1485.
  56. Vehmeijer FOL. (2019). Maternal psychological distress during pregnancy and childhood health outcomes: a narrative review. J Dev Orig Health Dis 10(3): 274-285.
  57. Verdejo-Roman J. et al. (2019). Maternal prepregnancy body mass index and offspring white matter microstructure: results from three birth cohorts. Int J Obes (Lond) 43(10): 1995-2006.
  58. Voerman E. and the LifeCycle Project-Maternal Obesity and Childhood Outcomes Study Group (2019). Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes. JAMA 321 (17): 1702-1715.
  59. Voerman E. et al. (2019). Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis. PLOS Medicine. Online first: 16(2): e1002744.
  60. Warrington N.M. et al. (2019). Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nat Genet 51(5): 804-814.
  61. Wiklund P. et al. DNA methylation links prenatal smoking exposure to later life health outcomes in offspring. Clin Epigenetics 11(1): 97.
  62. Wuttke M. et al. (2019). A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nat Genet 51(6): 957-972.
  63. Zou R. et al. (2019). Exposure to Maternal Depressive Symptoms in Fetal Life or Childhood and Offspring Brain Development: A Population-Based Imaging Study. Am J Psychiatry 176(9): 702-710.

2018

  1. Beaumont R.N. et al. (2018). Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Hum Mol Genet 27(4): 742-756.
  2. Björkqvist J. et al. (2018). Premature birth and circadian preference in young adulthood: evidence from two birth cohorts. Chronobiol Int 35(4): 555-564.
  3. Brand J.S. et al. (2018). Gestational diabetes and ultrasound-assessed fetal growth in South Asian and White European women: findings from a prospective pregnancy cohort. BMC Med 16(1): 203.
  4. Casas M. et al. (2018). The effect of early growth patterns and lung function on the development of childhood asthma: a population-based study. Thorax. Online first: 31 July 2018.
  5. Contreras Z.A., et al. (2018). Does early-onset asthma increase childhood obesity risk? A pooled analysis of 16 European cohorts. Eur Respir J. Online first: 52(3): 1800504.
  6. Demenais F. et al. (2018). Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nat Genet. 50(1): 42-53.
  7. den Dekker H.T. et al. (2018). Fetal and Infant Growth Patterns and Risk of Lower Lung Function and Asthma. The Generation R Study. Am J Respir Crit Care Med 197(2): 183-192.
  8. Felix J.F. and Cecil C.A.M. (2018). Population DNA methylation studies in the Developmental Origins of Health and Disease (DOHaD) framework. J Dev Orig Health Dis 10(3): 306-313.
  9. Felix J.F. et al. (2018). Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium. Int J Epidemiol 47(1): 22-3u.
  10. Gaillard R., Wright J. and Jaddoe V.W.V. (2018). Lifestyle intervention strategies in early life to improve pregnancy outcomes and long-term health of offspring: a narrative review. J Dev Ori Health Dis 10(3): 314-321.
  11. Golab B.P. et al. (2018). Influence of maternal obesity on the association between common pregnancy complications and risk of childhood obesity: an individual participant data meta-analysis. Lancet Child Adolesc Health 2(11): 812-821.
  12. Guxens M. et al. (2018). Air Pollution Exposure During Fetal Life, Brain Morphology, and Cognitive Function in School-Age Children. Biol Psychiatry 84(4): 295-303.
  13. Hamoen M et al. (2018). Dynamic prediction of childhood high blood pressure in a population-based birth cohort: a model development study. BMJ Open 8(11): e023912.
  14. Magnus M.C. et al. (2018). Vitamin D and risk of pregnancy-related hypertensive disorders: mendelian randomisation study. BMJ 361: k2167.
  15. McEachan R.R.C. et al. (2018). Availability, use of, and satisfaction with green space, and children’s mental wellbeing at age 4 years in a multicultural, deprived, urban area: results from the Born in Bradford cohort study. Lancet Planet Health 2(6): e244-e54.
  16. Parmar P. et al. (2018). Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults. EBioMedicine 38: 206-216.
  17. Peng C. et al. (2018). Residential Proximity to Major Roadways at Birth, DNA Methylation at Birth and Midchildhood, and Childhood Cognitive Test Scores: Project Viva (Massachusetts, USA). Environ Health Perspect 126(9): 97006.
  18. Santos S. et. al. (2018). Gestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania. BMC Medicine. Online first: 16 (201): 1-15.
  19. Santos S. et al. (2018). Sources of confounding in life course epidemiology. J Dev Ori Health Dis 10(3): 299-305.
  20. Sharp G.C. et al. (2018). Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts. Epigenomics 10 (1): 27-42.
  21. van Meel E.R. et al. (2018). A population-based prospective cohort study examining the influence of early-life respiratory tract infections on school-age lung function and asthma. Thorax 73 (2): 167-173.
  22. Viuff A.C. et al. (2018). Maternal depression during pregnancy and cord blood DNA methylation: findings from the Avon Longitudinal Study of Parents and Children. Transl Psychiatry 8(1): 244.
  23. Vogelezang S. et al. (2018). Infant breastfeeding and childhood general, visceral, liver, and pericardial fat measures assessed by magnetic resonance imaging. Am J Clin Nutr 108(4): 722-729.
  24. Waage J. et al. (2018). Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis. Nat Genet 50 (8): 1072-1080.
  25. Warrington N.M. et al. (2018). Maternal and fetal genetic contribution to gestational weight gain. Int J Obes (Lond) 42 (4): 775-784.
  26. Wilmink F.A. et al. (2018). Maternal blood pressure and hypertensive disorders during pregnancy and childhood respiratory morbidity: the Generation R Study. Eur Respir J. Online first: 52(5): 1800378.
  27. Zugna D. and Richiardi L. (2018). Effects decomposition in mediation analysis: a numerical example. Epidemiol Prev 42 (2): 127-133.

2017

  1. Elbert NJ et al. (2017). Allergenic food introduction and risk of childhood atopic diseases. PLoS One 12(11): e0187999.
  2. Herzog E.M. et al. (2017). Early- and late-onset preeclampsia and the tissue-specific epigenome of the placenta and newborn. Placenta 58: 122-132.
  3. Lubczynska M.J. et al. (2017). Exposure to elemental composition of outdoor PM2.5 at birth and cognitive and psychomotor function in childhood in four European birth cohorts. Environ Int 109: 170-180.
  4. Popovic M. et al. (2017). Increased correlation between methylation sites in epigenome-wide replication studies:impact on analysis and results. Epigenomics 9: 1489-1502.
  5. Rautio N. et al. (2017). Living environment and its relationship to depressive mood: A systematic review. Int J Soc Psychiatry 64 (1): 92-103.
  6. Richmond R.C. et al. (2017). Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study. PLoS Med 14 (1): e1002221.
  7. Sharp G.C. et al. (2017). Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium. Hum Mol Genet 26 (20): 4067-4085.
  8. van Meel E.R. et al. (2017). The role of respiratory tract infections and the microbiome in the development of asthma: A narrative review. Pediatr Pulmonol 52 (10): 1363-1370.

Funding

This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 733206. This website reflects only the authors' view and the European Commission is not responsible for any use that may be made of the information it contains.

© 2022 LifeCycle

Legal notice

LIFECYCLE Project

Get connected